Immune or not: a new Corona-infection possible?

A history of Covid-19-disease protects may not be always against re-infection with SARS-CoV-2. Meanwhile, several reports on convalescent Covid-19-patients were once again tested positive to the new Coronavirus, for discussions in the professional world. Currently, various causes are conceivable.

The case reports contradict the assumption that people should be after a Covid-19-disease of at least one to two years immune against re-infection. According to the opinion of most experts, however, it was not plausible that a re-infection had taken place. They discuss whether it may be for the cases may be a reactivation of the pathogen. To do this, the Virus in the body of an Infected outlast should, without in the nose and throat or other swab detectable. Only in the case of a weakening of the immune system, it would re-emerge – similar to the for example, in the case of cold sores or shingles happens.

“It is still unclear, what we see there,” said Professor Dr. Lothar Wieler, President of the Robert Koch Institute. Another possible explanation of the phenomenon is that the first test result was false negative. Another possibility is that Covid-19 patients surviving disease for a while, a virus genome of SARS-CoV-2 left the no longer be contagious.

At the moment no one knows whether all the people who have recovered from Covid-19-patients were immune to SARS-CoV-2, and how long the immunity, where appropriate, to stop. For this purpose there are only hints of other corona viruses. “If people are immune, it would be great to know this,” said Wieler. Currently, but about the immunity status of Recovering is still too little known.

on/PZ/RF

Sources: DOI 10.1001/jama.2020.2783 DOI 10.1093/cid/ciaa398/5817588

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