Membrane stripping: Risks and effectiveness for inducing labor

In uncomplicated pregnancies, membrane stripping at 38โ€“40 weeks of gestation will often:

  • increase the rate of spontaneous vaginal labor
  • reduce the need for other induction methods, such as medication
  • decrease the likelihood of the pregnancy lasting beyond 41 weeks

The procedure aims to separate the amniotic sac and fine fetal membranes from the uterine wall. This separation triggers the release of natural chemicals called prostaglandins. Prostaglandins help soften the cervix and stimulate contractions and labor.

What to expect before and after

Women do not generally need to prepare for membrane stripping, which the doctor will carry out as part of a regular examination.

The procedure usually takes place in a doctor’s office. The doctor may need to stimulate the cervix to dilate it, as membrane stripping will not be possible otherwise.

The procedure can be uncomfortable, and most women feel a bit of pain and tenderness afterward. Some women also experience minor bleeding.

It is essential to let the doctor know immediately if severe pain or bleeding occurs during or after the appointment.

In most cases, membrane stripping increases the likelihood of spontaneous labor, especially within the first 7 days following the procedure.

Doctors usually only need to carry out the procedure once to induce labor successfully. However, some women may require multiple stripping procedures.

A 2014 study looking at the efficacy and safety of membrane stripping found that it reduced total gestation time.

The study, which included 80 women who had the procedure and 80 who did not, showed that:

  • Of the women who received membrane stripping, 90 percent went into spontaneous labor compared to 75 percent of those who did not have the procedure.
  • Only 10 percent of the women who received membrane stripping were still pregnant at 41 weeks of gestation compared to 25 percent of those who did not.
  • Membrane stripping did not affect the risk of maternal or fetal complications.

Another study of 800 women found that membrane stripping:

  • reduced the time between induction and labor
  • increased the vaginal delivery rate
  • lowered the need for oxytocin, a drug that induces labor

However, the researchers also used other methods of induction alongside the membrane stripping.


Membrane stripping takes place during the final few weeks of pregnancy, which are usually between 38 and 41 weeks of gestation.

Membrane stripping is a relatively safe procedure in uncomplicated pregnancies, and study results have shown that it can increase the likelihood of spontaneous labor.

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